Morphokinetics as a predictor of self-correction to diploidy in tripronucleated intracytoplasmic sperm injection–derived human embryos
نویسندگان
چکیده
منابع مشابه
The role of sperm aneuploidy as a predictor of the success of intracytoplasmic sperm injection?
BACKGROUND We present the first powered prospective study to assess whether sperm aneuploidy can predict the outcome of ICSI. METHODS Our null hypothesis was that aneuploidy rates (AR) are identical in men who achieve successful (Group A) and unsuccessful (Group B) ICSI outcome. A power calculation yielded a sample number of 56 to achieve 80% power to reject our hypothesis at the 5% significa...
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BACKGROUND Time-lapse observation presents an opportunity for optimizing embryo selection based on morphological grading as well as providing novel kinetic parameters, which may further improve accurate selection of viable embryos. The objective of this retrospective study was to identify the morphokinetic parameters specific to embryos that were capable of implanting. In order to compare a lar...
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A total of 41 patients requested thawing of supernumerary embryos in an intracytoplasmic sperm injection (ICSI) programme. Mean patient age was 30.8 +/- 3.8 years. Embryo freezing by the ultrarapid method was performed at room temperature in 3 mol/l DMSO and 0.25 mol/l sucrose. Total freezing time was 2.5 min including filling of the straw. In the thawing process, the embryos were removed from ...
متن کاملSperm quality may adversely affect the chromosome constitution of embryos that result from intracytoplasmic sperm injection.
OBJECTIVE To determine whether the high rate of chromosomal abnormalities in the embryos of an infertile couple were caused by a paternal factor that may have involved the sperm centriole. DESIGN Case report. SETTING Private IVF program. PATIENT(S) An infertile couple who underwent IVF-ET because of severe male factor infertility and endometriosis. INTERVENTION(S) Preimplantation geneti...
متن کاملHuman Sperm Aster Formation and Chromatin Configuration in Rabbit Oocytes Following Intracytoplasmic Sperm Injection Using a Piezo-Micromanipulator
In human fertilization, the sperm centrosome nucleates a radial array of microtubules called the sperm aster. The sperm aster is responsible for apposition of male and female pronuclei, and later gives rise to the first meiotic spindle. The objective of this study was to determine microtubule assembly and chromatin configuration in rabbit oocytes following intracytoplasmic injection with human ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2015
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2015.05.024